Effects of Endogenous PPAR Agonist Nitro-Oleic Acid on Metabolic Syndrome in Obese Zucker Rats

Figure 1

Food intake in male 4-mo-old obese Zucker rats (obese) over 14 days of infusion with vehicle, OA-NO₂, or OA, each at 7.5 𝜇g/kg/d via osmotic mini-pumps. Age and gender matched lean rats with vehicle treatment were used as controls. Lean: 𝑛=3; Vehicle: 𝑛=7; OA-NO₂: 𝑛=5; OA: 𝑛=5. *, 𝑃<.01 versus Obese/Vehicle; ^#, 𝑃<.05 versus OA during the corresponding period. Data are mean ± SE.