Protective Effects of Peroxisome Proliferator-Activated Receptor-α Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes

Figure 1

(a) ALT in different groups (Mean ± SD, 𝑛=6). After 4 h of hepatocellular hypoxia and 10 h of reoxygenation. The levels of ALT in hepatocytes medium were determined. ^c𝑃<0.01 versus control group; ^e𝑃<0.05, ^f𝑃<0.01 versus H/R group. (b) AST in different groups (Mean ± SD, 𝑛=6). After 4 h of hepatocellular hypoxia and 10 h of reoxygenation. The levels of AST in hepatocytes medium were determined. ^c𝑃<0.01 versus control group; ^f𝑃<0.01 versus H/R group. (c) MDA in different groups (Mean ± SD, 𝑛=6). After 4 h of hepatocellular hypoxia and 10 h of reoxygenation. The levels of MDA in hepatocytes determined.^c𝑃<0.01 versus control group; ^f𝑃<0.01 versus H/R group.

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