Role of Peroxisome Proliferator-Activated Receptor <svg     style="vertical-align:-3.69pt;width:33.862499px;" id="M1" height="20.475" version="1.1" viewBox="0 0 33.862499 20.475" width="33.862499"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
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</svg> and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells

<table>Effects of <svg height="16.6625" id="M113" style="vertical-align:-3.56265pt" version="1.1" viewbox="0 0 70.824997 16.6625" width="70.824997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> and <i>BCL-6</i> knockdown on Miapaca-2 gene expression. Miapaca-2 cells were transiently infected with nontargeting control, <i>hBCL-6</i> or <svg height="12.4375" id="M114" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 8.8999996 12.4375" width="8.8999996" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,12.162)"><path d="M499 88q-41 -46 -83.5 -73t-68.5 -27q-41 0 -19 98l52 225q10 43 8 59.5t-16 16.5q-37 0 -112 -65t-117 -135q-14 -42 -38 -179q-36 -7 -75 -20l-7 8l127 594q8 40 2.5 49t-35.5 9h-35l5 25q36 3 71.5 13t56.5 18t25 8q11 0 3 -38l-88 -417h2q77 102 195 167q44 24 79 24
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</svg> <svg height="16.6625" id="M115" style="vertical-align:-3.56265pt" version="1.1" viewbox="0 0 70.824997 16.6625" width="70.824997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,12.162)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
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t-115.5 -72q40 -86 66 -133q39 -68 65 -101q28 -37 73 -51zM491 483q0 67 -33.5 101t-91.5 34q-35 0 -51 -10q-13 -8 -20 -48l-45 -245h49q71 0 113 28q79 52 79 140z" id="x1D445"></path></g><g transform="matrix(.017,-0,0,-.017,45.092,12.162)"><path d="M558 587q0 -32 -14 -61t-40 -53.5t-48.5 -41t-54.5 -36.5q144 -51 144 -174q0 -55 -43.5 -108t-104.5 -87q-77 -42 -131 -42q-31 0 -54 20t-31 47l11 18q48 -29 108 -29q79 0 119.5 43t40.5 109t-44.5 107.5t-119.5 50.5l22 47q34 1 65 21q96 61 96 157q0 42 -24 67.5
t-62 25.5q-24 0 -43.5 -9t-35 -29.5t-27 -44t-22.5 -63t-19.5 -75.5t-18.5 -91q-57 -294 -68 -380q-26 -190 -35 -200q-26 -31 -97 -37l-4 26q19 9 48 170l77 413q23 121 52.5 187.5t83.5 114.5q70 62 148 62q51 0 88.5 -34t37.5 -91z" id="x1D6FD"></path></g><g transform="matrix(.017,-0,0,-.017,54.968,12.162)"><path d="M368 703l-264 -866h-60l265 866h59z" id="x2F"></path></g><g transform="matrix(.017,-0,0,-.017,61.972,12.162)"><path d="M494 514l-10 -15q-56 76 -106.5 117t-110.5 41q-45 0 -45 -30q0 -28 109 -152q59 -68 86 -118.5t27 -107.5q0 -62 -29.5 -119.5t-86.5 -96.5q-64 -45 -138 -45q-76 0 -121.5 53t-45.5 136q0 74 40.5 135t98.5 95q43 26 87 42q-40 59 -57.5 92t-17.5 62q0 46 39 77.5
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</svg><i>-</i>specific shRNAs and then stimulated with human <svg height="11.825" id="M116" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 46.525002 11.825" width="46.525002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,11.55)"><path d="M649 676l-22 -187l-33 -2q3 56 -12 94q-8 20 -31.5 26.5t-86.5 6.5h-74l-90 -491q-4 -23 -6 -36.5t1 -25t7 -16.5t18 -9t27 -5t41 -3l-6 -28h-286l4 28q68 5 84 18.5t28 76.5l94 491h-55q-74 0 -100.5 -6t-41.5 -23q-24 -29 -54 -98l-32 1q32 98 53 188h22q7 -18 15 -22
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t29.5 81.5l72 387l7.5 40.5t1 26.5t-4 18t-15.5 10t-24 6t-37 4l8 28h461z" id="x1D439"></path></g><g transform="matrix(.017,-0,0,-.017,36.814,11.55)"><path d="M545 106q-67 -118 -134 -118q-24 0 -40 37.5t-30 129.5h-2q-47 -72 -103 -119.5t-108 -47.5q-47 0 -76 45.5t-29 119.5q0 113 85 204t174 91q47 0 70 -33.5t43 -119.5h3q32 47 80 140l55 13l10 -9q-47 -80 -138 -201q17 -99 27.5 -136t22.5 -37q23 0 69 61zM333 204
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</svg> with or without GW501516 for 24 hours. Total mRNA was isolated and gene expression was determined using qRT-PCR. Data is normalized to <svg height="16.6625" id="M117" style="vertical-align:-3.56265pt" version="1.1" viewbox="0 0 10 16.6625" width="10" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,12.162)"><path d="M558 587q0 -32 -14 -61t-40 -53.5t-48.5 -41t-54.5 -36.5q144 -51 144 -174q0 -55 -43.5 -108t-104.5 -87q-77 -42 -131 -42q-31 0 -54 20t-31 47l11 18q48 -29 108 -29q79 0 119.5 43t40.5 109t-44.5 107.5t-119.5 50.5l22 47q34 1 65 21q96 61 96 157q0 42 -24 67.5
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</svg>-actin and indicated as fold change.</table>

PPAR Research

fig3

Figure 3

Figure 3: Role of Peroxisome Proliferator-Activated Receptor <svg     style="vertical-align:-3.69pt;width:33.862499px;" id="M1" height="20.475" version="1.1" viewBox="0 0 33.862499 20.475" width="33.862499"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
			<g transform="matrix(.022,-0,0,-.022,.062,15.825)"><path id="x1D737" d="M54 -114l114 487q24 102 62.5 165t102.5 109q53 38 129 38q51 0 86 -33.5t35 -84.5q0 -57 -31.5 -105t-81.5 -68v-2q88 -14 88 -126q0 -64 -29 -127q-29 -62 -90 -107q-62 -44 -143 -44q-67 0 -97 18l-28 -124q-11 -51 -26 -87h-117q9 19 26 91zM304 480l-87 -393
q0 -29 19 -44t48 -15q63 0 110 74q46 74 46 153q0 117 -52 117q-6 0 -23.5 -3t-21.5 -3q-33 0 -33 25q0 15 15 25.5t41 10.5q8 0 30 -6q27 -5 28 -5q26 0 41 43t15 89q0 39 -17.5 62t-44.5 23q-46 0 -71 -35.5t-43 -117.5z" /></g><g transform="matrix(.022,-0,0,-.022,12.504,15.825)"><path id="x2F" d="M368 703l-264 -866h-60l265 866h59z" /></g><g transform="matrix(.022,-0,0,-.022,21.739,15.825)"><path id="x1D739" d="M44 169v1q0 90 67 166q68 79 170 95q-104 54 -104 124q0 64 57 97t135 33q47 0 95 -17q47 -17 47 -46q0 -62 -59 -62q-23 0 -40.5 12.5t-26.5 28t-25.5 28t-39.5 12.5q-68 0 -68 -56q0 -39 101 -90q37 -18 64 -34t58 -41t47 -58t16 -72q0 -125 -92 -212q-92 -86 -216 -86
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</svg> and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells 

Figure 3 | Role of Peroxisome Proliferator-Activated Receptor 
	
		
			

		
	
 and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells 

PPAR Research

Role of Peroxisome Proliferator-Activated Receptor and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells

Figure 3