Research Article

Timcodar (VX-853) Is a Non-FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses Adipogenesis

Table 1

Primer sequences.

Primer nameForward sequence Reverse sequence

GRαAAAGAGCTAGGAAAAGCCATTGTCTCAGCTAACATCTCTGGGAATTCA
GRβAAAGAGCTAGGAAAAGCCATTGTCCTGTCTTTGGGCTTTTGAGATAGG
PDK4TTTCTCGTCTCTACGCCAAGGATACACCAGTCATCAGCTTCG
GILZAATGCGGCCACGGATGGGACTTCACGTTTCAGTGGACA
p21TGAATGGAGACAGAGACCCCAGGAACAGGTCGGACATCACC
PPARγ2AAACTCTGGGAGATTCTCCTGTTGGAAGTGCTCATAGGCAGTGCA
C/EBPαAGAGCCGAGATAAAGCCAACAGCAGGCGGTCATTGTCACT
PREF-1CGGGAAATTCTGCGAAATAGTGTGCAGGAGCATTCGTACT
C/EBPβTTATAAACCTCCCGCTCGGCTTCCATGGGTCTAAAGGCGG
FASNGCTGCTGTTGGAAGTCAGCAGTGTTCGTTCCTCGGAGTG
SREBP1CACCAGCATAGGCGAAGGAAGTGTGCGGCCTGTGGAT
SCD1GTACCGCTGGCACATCAACTAACTCAGAAGCCCAAAGCTCA
FABP4GTCACAGCACCCTCCTGAAAGGCAAAGCCCACTCCTACTT
GAPDHCAATGTGTCCGTCGTGGATCTGTCCTCAGTGTAGCCCAAGATG