Caffeoylquinic Acid-Rich Extract of Aster glehni F. Schmidt Ameliorates Nonalcoholic Fatty Liver through the Regulation of PPARδ and Adiponectin in ApoE KO Mice

Figure 2

Effects of Aster glehni extract on diet intake amount, drinking water intake amount, body weight, abdominal adipose tissue weight, serum triglyceride, and serum adiponectin, total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol in ApoE KO mice administered with 0.15% cholesterol diet. ((a) and (b)) Diet and drinking water intake amounts were estimated for four weeks. (c) Body weight of mice was estimated just prior to sacrifice. (d) Abdominal adipose tissue was removed from sacrificed mice and weighed. (e) Triglyceride concentration in serum was estimated with triglyceride colorimetric assay kit. (f) Adiponectin concentration in serum was estimated with mouse adiponectin enzyme-linked immunosorbent assay (ELISA) kit. (g, h, and i) Levels of cholesterols were estimated with triglyceride colorimetric assay kit. The results are expressed as means ± SEM. Values were statistically analyzed by unpaired -test and one way ANOVA. All experiments were repeated three times. versus control, versus control, and versus control.

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