Research Article
Expression of GPR43 in Brown Adipogenesis Is Enhanced by Rosiglitazone and Controlled by PPARγ/RXR Heterodimerization
Figure 1
Rosiglitazone treatment induces the increase of GPR43 transcription during the adipogenesis of brown adipocytes. (a) mRNA transcription levels of GPR43 during the differentiation of IM-BAT adipocytes measured by quantitative real-time PCR. (b and c) Comparison of GPR43 (b) and UCP-1 (c) mRNA levels in mature IM-BAT adipocytes and 3T3-L1 adipocytes after 7 days of differentiation. (d) IM-BAT cells were differentiated with or without rosiglitazone (1 μM) from day 3 to day 7 before GPR43 and aP2 mRNA levels were measured on day 7 after differentiation. Data are expressed as mean ± SEM (). and by Student’s -test.
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