Treatment of Diabetic Mice with a Combination of Ketogenic Diet and Aerobic Exercise via Modulations of PPARs Gene Programs

Figure 2

Ketogenic diet and ketogenic diet combined with exercise improve insulin sensitivity in diabetic mice. (a) Mice fasting blood glucose, (b) GTT, (C) ITT, (d) HbA1c levels, (e) serum glucose, (f) insulin levels, and (g) HOMA-IR indexes in the diabetes, diabetes + KD, and diabetes + KD + AE groups, after 6-week intervention. Data were presented as means ± SEM ( per group) and statistical analysis was performed with 1-way ANOVA. versus diabetic group.

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