Rosiglitazone, a Ligand to PPAR, Improves Blood Pressure and Vascular Function through Renin-Angiotensin System Regulation

Figure 1

Effect of rosiglitazone (RGZ) on noradrenaline (NA)-induced aortic reactivity in absence (a) or presence (b) of N(ω)-nitro-L-arginine-methyl-ester (L-NAME, 300μM). The values represent the mean ± SEM (n=6 animals per group). One-way analysis of variance (ANOVA) post Tukey. ⁺P < 0.05 sham-V vs. sham-RGZ, ^∗P < 0.05 sham-V vs. AoCo-V, ^#P < 0.05 AoCo-V vs. AoCo-RGZ.

(a)

(b)