The Model of PPARγ-Downregulated Signaling in Psoriasis

Figure 6

Evaluation of PPARγ-downregulated subnetwork (selected PPARγ regulators and targets) associated with psoriasis using microarray data analysis (results of differential expression analysis of psoriatic lesions vs. unaltered lesions). The saturation in blue indicates the degree of gene downexpression in psoriatic samples in comparison with unaltered samples. The saturation in red indicates the degree of gene overexpression. The list of targets and regulators can be seen in supplemental materials, “PPARG regulators and targets,” list 3.