PPAR<i>α</i> Agonist WY-14643 Relieves Neuropathic Pain through SIRT1-Mediated Deacetylation of NF-<i>κ</i>B

<div>Repeated WY-14643 administration alleviated NP in CCI rats by activating PPAR<i>α</i>. (a) WY-14643 increased the PWMT of CCI rats, but GW6471 and si-SIRT1 reversed this effect. (b) WY-14643 increased the PWTL of CCI rats, but GW6471 and si-SIRT1 reversed this effect.</div>

PPAR Research

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Figure 2: PPAR<i>α</i> Agonist WY-14643 Relieves Neuropathic Pain through SIRT1-Mediated Deacetylation of NF-<i>κ</i>B 

PPAR Research

PPARα Agonist WY-14643 Relieves Neuropathic Pain through SIRT1-Mediated Deacetylation of NF-κB

Figure 2