Research Article

Nonclassical Axis of the Renin-Angiotensin System and Neprilysin: Key Mediators That Underlie the Cardioprotective Effect of PPAR-Alpha Activation during Myocardial Ischemia in a Metabolic Syndrome Model

Figure 5

Effect of fenofibrate administration on myocardial aminopeptidase N (APN) expression in myocardial tissue from the control (CT) and metabolic syndrome (MetS) animals. (a) Representative image. (b) Angiotensin IV concentration. (c) Insulin-regulated aminopeptidase (IRAP) protein expression. The values show the ( per group). vs. CT-Sh; Δ vs. CT-Sh; Σ vs. MetS-Sh; # vs. CT-MI-V; ω vs. CT-MI-V; & vs. MetS-MI-V. Analysis of variance-Newman-Keuls.
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