The PPAR Ω Pocket: Renewed Opportunities for Drug Development

Figure 3

Sequence alignment of the H2-H3 region of the human PPARs, annotated with experimentally observed Ser/Thr/Tyr phosphorylations (red) and Lys acetylations (blue) [152] and with the same PTMs predicted using the tools [147–151] listed in Section 4 (orange and green, respectively). Notably, the employed tools also identified the experimentally observed PTMs.