PPARγ Plays an Important Role in Acute Hepatic Ischemia-Reperfusion Injury via AMPK/mTOR Pathway

Figure 3

Effect of PPARγ upregulation on liver function and pathology of mice in IR. Notes: (a) the levels of serum ALT and AST (, means for Rosi versus IR after 2, 6, 12, and 24 h, + means for IR verse control); (b) the levels of serum TNF-α and IL-1β (, means for Rosi versus IR after 2, 6, 12, and 24 h, + means for IR verse control); (c) relative mRNA expression of TNF-α (, # means for Rosi versus IR after 2, 6, 12, and 24 h, + means for IR verse control); (d) relative mRNA expression of Bax (, # means for Rosi versus IR after 2, 6, 12, and 24 h, + means for IR verse control); (e) protein expression of PPARγ, TNF-α, IL-1β, Bax, and cleaved caspase9 (, # means for si-PPARγ versus IR after 2, 6, 12, and 24 h, means for IR verse control).

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