Research Article

Fenofibrate Exerts Antitumor Effects in Colon Cancer via Regulation of DNMT1 and CDKN2A

Figure 4

Fenofibrate inhibited cell migration and EMT. (a) Wound healing assay for demonstrating the inhibitory effect of fenofibrate on the migration of colon cancer cells at 0, 24, 48, and 72 h following wounding. (b) The mRNA and protein expression levels of E-cadherin, vimentin, and MMP9 were measured following fenofibrate treatment. Data was presented as (, , ). (c) The expression of E-cadherin and vimentin in colon cancer cells was examined using immunofluorescence staining (magnification 200x).
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