PPARα Gene Is Involved in Body Composition Variation in Response to an Aerobic Training Program in Overweight/Obese
Table 4
Distribution test between the polymorphism in Intron 7 G/C (rs 4253778) of the PPARα gene and responders and nonresponders to weight loss training program.
Variables
PPARα
McNemar test
RR (95% IC)
CC (%)
CA+AA (%)
△weight
0.150
0.80 (0.27–2.31)
Responders
16 (59.3)
20 (64.5)
Nonresponders
11 (40.7)
11 (35.5)
△BMI
0.200
0.92 (0.32–2.63)
Responders
16 (59.3)
19 (61.3)
Nonresponders
11 (40.7)
12 (38.7)
△LM
0.122
1.44 (0.49–4.21)
Responders
18 (66.7)
18 (33.3)
Nonresponders
9 (58.1)
13 (41.9)
△FM
0.003
0.21 (0.05–0.90)
Responders
18 (66.7)
28 (90.3)
Nonresponders
9 (33.3)
3 (9.7)
△ %FM
0.002
0.68 (0.19–2.36)
Responders
20 (74.1)
25 (80.6)
Nonresponders
7 (25.9)
6 (19.4)
△WC
0.009
0.48 (0.14–1.59)
Responders
18 (66.7)
25 (80.6)
Nonresponders
9 (33.3)
6 (19.4)
△abdomen
0.000
0.84 (0.21–3.30)
Responders
22 (81.5)
26 (83.9)
Nonresponders
5 (18.5)
5 (16.1)
△HC
0.001
0.42 (0.10–1.64)
Responders
20 (74.1)
27 (87.1)
Nonresponders
7 (25.9)
4 (12.9)
Data are frequency of responders (who obtained some weight loss) and nonresponders (who did not lose weight or increased any variable related to weight loss). : number of participants; △: variation between pre- and postintervention; BMI: body index mass; FM: fat mass; %FM: fat mass percentage; WC: waist circumference; HC: hip circumference. Chi-square test (McNemar test).
