Pregabalin for Refractory Radicular Leg Pain due to Lumbar Spinal Stenosis: A Preliminary Prospective Study

Table 3

Adverse events.

Age/sex	Event	PGB dose at onset; (mg/day)	Onset; (days after PGB prescription)	Severity	Causal association	PGB prescription	Special treatment
76/M	Rash	25 mg 1; (25)	5	Mild	Unclear	Withdrawn	No
76/F	Dizziness	25 mg 2; (50)	14	Mild	Yes	Withdrawn	No
79/M	Nausea	50 mg 2; (100)	30	Mod.	Yes	Withdrawn	No
79/M	Ataxia	50 mg 2; (100)	30	Mod.	Yes	Withdrawn	No
79/M	Somnolentia	25 mg 2; (50)	10	Mild	No	Dose decreased	No
81/M	Increased numbness	75 mg 2; (150)	25	Mod.	Unclear	Withdrawn	No
82/M	Increased numbness	25 mg 1; (25)	14	Mod.	Unclear	Withdrawn	No
78/F	Fever	75 mg 2; (150)	33	Mod.	Unclear	Withdrawn	No; (blood test)
78/F	Nausea	75 mg 2; (150)	33	Mod.	Unclear	Withdrawn	No
64/F	Ataxia	50 mg 2; (100)	14	Mod.	Yes	Dose decreased	No
64/F	Dizziness	50 mg 2; (100)	14	Mod.	Yes	Dose decreased	No
64/F	Nausea	50 mg 2; (100)	14	Mod.	Yes	Dose decreased	No
64/M	Rash	25 mg 1; (25)	6	Mod.	Unclear	Withdrawn	No
71/F	Somnolentia	25 mg 2; (50)	16	Mild	Yes	Continued	No
71/F	Ataxia	25 mg 2; (50)	16	Mild	Yes	Continued	No
54/F	Weight gain	—	231	—	Unclear	Withdrawn	—
73/F	Edema	—	140	Mild	Yes	Dose decreased	No
74/M	Edema	150 mg 2; (300)	35	Mild	Yes	Dose decreased	No

Mod.: moderate.