Research Article

Antinociceptive Effect of Intrathecal Injection of Genetically Engineered Human Bone Marrow Stem Cells Expressing the Human Proenkephalin Gene in a Rat Model of Bone Cancer Pain

Table 2

Cell activity after freezing and recovering (%, ).

Cell typehBMSC P3pBABE-hBMSChPPE-hBMSC value value

Number ()555
Living cell rate (%)89.90 ± 3.2087.30 ± 3.2688.08 ± 2.201.0330.386

There were no significant differences among the three groups (P > 0.05), indicating that transfection had no effect on the morphology and proliferation of these cells. hPPE, human proenkephalin; hBMSC, human bone marrow stem cell; pBABE-hBMSC, the pBABE-hBMSC group; hPPE-hBMSC, the hPPE-hBMSC group.