Effects of Glutathione on Mechanical Allodynia and Central Sensitization in Chronic Postischemic Pain Rats

Figure 3

Withdrawal threshold in CPIP and sham rats. Rats in the sham and CPIP groups received saline. Rats in the CPIP + GSH 100, CPIP + GSH 200, and CPIP + GSH 500 groups received GSH 100 mg/kg, 200 mg/kg, and 500 mg/kg, respectively. CPIP: chronic postischemia pain; GSH: glutathione. , repeated measurements ANOVA followed by the Tukey test compared to the sham group. , repeated measurement ANOVA followed by the Tukey test compared to the CPIP group. , repeated measurement ANOVA followed by the Tukey test compared to the CPIP + GSH 100 group.

(a) Ipsilateral paw

(b) Contralateral paw