Serum Analysis in Patients with Temporomandibular Disorders: A Controlled Cross-Sectional Study in Norway

Table 1

Serum analyses resulted in nineteen different determinants common in diagnostics. Second column shows normal values for women and men at all ages. Most TMD patients and controls had values within normal biologic range. TMD patients had significantly higher values of hemoglobin (), cobalamin (), albumin (), PTH (), and vitamin D () and significantly lower values of creatinine () and potassium () compared to controls.

Serum analyses	Reference values	TMD			Control			-value (paired t-test)
		Mean	±SD	Range	Mean	±SD	Range	( = sign.)
Hemoglobin	W: 11.7–15.3, M: 13.4–17.0 g/dL	14.1	1.28	8.1, 16.2	13.8	0.83	11.5, 16	0.036
EVF	W: 0.35–0.46, M: 0.40–0.50	0.41	0.04	0.28, 0.48	0.41	0.02	0.35, 0.48	0.325
MCV	82–98	91.2	4.66	76, 102	90.1	3.62	83, 100	0.299
Homocysteine	<15 umol/L	11.1	3.79	5.8, 28.0	11.3	3.03	5.7, 24.2	0.459
Transferrin R	W: 1.9–4.4, M: 2.2–5.0 mg/L	3.27	1.78	1.7, 14.6	2.98	0.80	1.7, 5.9	0.103
TSH	0.4–4.5 mlE/L	1.63	0.83	0.01, 4.31	1.80	0.98	0.14, 4.72	0.191
FT4	9.5–22.0 pmol/L	16.0	3.13	7.8, 29	15.7	2.26	11.5, 27.0	0.266
Cobalamin	175–700 pmol/L	422	194.8	167, 1322	363	124.9	129, 702	0.023
Folate	>8 nmol/L	20.7	10.41	7.7, 45.3	20.2	7.38	7.5, 45.3	0.450
CRP (<1 = 1)	<5 mg/L	2.43	3.09	1.0, 14.0	2.10	2.84	1.0, 20.0	0.268
Creatinine	W: 45–90, M: 60–105 umol/L	65.6	10.47	45, 93	69.7	12.14	49, 108	0.006
Estimated GFR	>90 mL/min/l	>60	—	—	>60	—	—	—
Sodium	137–145 mmol/L	140.1	1.48	137, 144	140.0	1.39	136, 144	0.227
Potassium	3.5–5.0 mmol/L	4.0	0.25	3.2, 4.6	4.1	0.31	3.4, 5.3	0.011
Calcium	2.20–2.55 mmol/L	2.40	0.09	2.21, 2.63	2.40	0.08	2.15, 2.59	0.456
GT	W: <40y = 10–45, >40y = 10–75 U/L M:<40y = 10–80, >40y = 15–115 U/L	22.2	19.63	8.0, 145.0	17.9	12.20	6.0, 72.0	0.078
Albumin	<39y: 39–50, 40–69y: 39–48, >70y: 36–48 g/L	46.3	2.94	40.0, 53.0	45.1	1.96	40.0, 49.0	0.005
PTH	1.3–6.8 pmol/L	3.4	1.53	0.9, 8.2	2.9	1.09	1.0, 6.0	0.038
Vitamin D	50–113 nmol/L	72.4	26.93	19.0, 187.0	61.1	18.68	22.0, 127.0	0.005