Electroacupuncture Treatment Suppresses Transcription Factor IRF8 in Spinal Cord of Rats with Spared Nerve Injury

Figure 4

Immunofluorescence staining detected the effect of 2 Hz EA on coexpression of spinal IRF8 with CD11b in SNI rats. IRF8 and CD11b were double-stained in the spinal dorsal horn from the sham, SNI, and SNI + EA group rats (scale bar = 20 μm). Immunofluorescence staining results showed that SNI enhanced spinal IRF8 and CD11b expression compared with the sham group. 2 Hz EA treatment reversed the coexpression of IRF8 (green) with microglial activation indicator CD11b (red) in the spinal cord of SNI rats.