Tapentadol Prolonged Release for Severe Chronic Osteoarthritis Pain in the Elderly—A Subgroup Analysis of Routine Clinical Practice Data

Table 7

Most frequently reported adverse drug reactions (incidences of >1% of patients for each preferred term).

	Patients aged >65 years (n = 752)	Patients aged ≤65 years (n = 282)
Any adverse drug reaction	63 (8.4%)	18 (6.4%)
Gastrointestinal disorders	33 (4.4%)	12 (4.3%)
Nausea	20 (2.7%)	8 (2.8%)
Constipation	8 (1.1%)	1 (0.4%)
Nervous system disorders	24 (3.2%)	8 (2.8%)
Dizziness	11 (1.5%)	6 (2.1%)

Data are number of patients (%).