Low Incidence of Postoperative Respiratory Depression with Oliceridine Compared to Morphine: A Retrospective Chart Analysis

Figure 4

Incidence of opioid-induced respiratory depression in high-risk subgroup (secondary outcome). High-risk patients were defined as patients who were obese, or with a comorbid medical diagnosis of chronic obstructive pulmonary disease, renal impairment, or sleep apnea, or who were elderly (age ≥ 65 years at the time of treatment). Incidence of respiratory events was significantly lower in the oliceridine cohort in the high-risk subgroup.