The Effectiveness of Cancer Pain Management in a Tertiary Hospital Outpatient Pain Clinic in Thailand: A Prospective Observational Study

Table 3

Pain interference rating by BPI and other symptoms’ rating per ESAS.

	BL (n = 72)	FU1 (n = 72)	FU2 (n = 72)	FU3 (n = 72)	value (Friedman test)
BPI, pain interference, median (IQR)
General activity	6.0 (3.5–8.0)	4.0 (0.0–7.0)	4.5 (1.0–7.0)	5.0 (0.0–7 .0)	0.004
Mood	5.5 (2.0–8.0)	5.0 (1.0–7.0)	3.0 (0.0–6.5)	3.0 (0.0–6.5)	0.012
Walking ability	5.0 (2.5–8.0)	5.0 (0.0–8.0)	5.0 (0.0–8.5)	5.0 (0.0–8.0)	0.191
Normal work	6.0 (3.0–9.0)	4.5 (0.0–9.0)	5.0 (0.5–9.0)	5.0 (0.0–8.0)	0.407
Relations with others	4.5 (1.0–7.0)	2.0 (0.0–5.0)	3.0 (0.0–5.0)	1.5 (0.0–4.5)	0.002
Sleep	7.0 (4.0–8.0)	5.0 (0.0–7.5)	4.0 (0.0–7.0)	2.5 (0.0–6.0)	<0.001
Enjoyment of life	5.0 (2.0–8.0)	5.0 (2.0–8.0)	4.5 (0.5–7.5)	3.5 (0.0–6.0)	0.017
BPI total score	40.0 (26.0–52.0)	29.5 (15.0–44.0)	30.0 (14.0–46.0)	26.0 (8.5–40.5)	<0.001
ESAS, symptoms, median (IQR)
Pain	4.0 (2.5–6.0)	4.0 (2.0–5.5)	3.0 (1.0–6.0)	3.0 (1.0–5.5)	<0.001
Fatigue	5.0 (2.0–6.0)	5.0 (2.0–6.0)	4.0 (0.0–6.0)	4.5 (2.0–6.0)	0.173
Nausea	0.0 (0.0–3.0)	0.0 (0.0–2.0)	0.0 (0.0–1.0)	0.0 (0.0–1.5)	0.152
Depression	0.0 (0.0–3.0)	0.0 (0.0–2.0)	0.0 (0.0–2.5)	0.0 (0.0–2.5)	0.712
Anxiety	3.0 (0.0–5.0)	2.0 (0.0–3.0)	1.0 (0.0–5.0)	1.0 (0.0–5.0)	0.204
Drowsiness	3.0 (0.5–5.0)	2.0 (0.0–5.0)	2.0 (0.5–4.0)	2.0 (0.0–5.5)	0.806
Appetite	4.0 (0.0–7.0)	3.0 (0.05.0)	3.0 (0.0–5.0)	2.5 (0.0–5.0)	0.094
Well-being	4.5 (0.0–6.5)	4.0 (0.5–5.0)	2.0 (0.0–5.0)	3.0 (0.0–6.0)	0.729
Shortness of breath	2.0 (0.0–5.0)	2.0 (0.0–5.0)	1.0 (0.0–4.5)	1.0 (0.0–5.0)	0.438
ESAS total score	27.5 (17.0–43.0)	23.0 (12.0–36.0)	17.5 (10.5–32.0)	23.5 (10.5–36.5)	0.011

at follow-up compared to baseline using Wilcoxon signed-rank test. FU: follow-up; BPI: Brief Pain Inventory; ESAS: Edmonton Symptom Assessment System.