Review Article

Revisiting the Corneal and Blink Reflexes for Primary and Secondary Trigeminal Facial Pain Differentiation

Table 2

Situations of corneal sensation alterations that may limit the use of corneal reflex if present concurrently with trigeminal neuralgia.

Infectious diseases
 Type 1 herpes simplex
 Varicella zoster virus
Mycobacterium leprae
 Fungal infections
Autoimmune disorder
 Diabetes mellitus
 Grave’s disease
 Sjögren’s syndrome
Ophthalmic procedures and surgeries
 Corneal transplant
 Laser and other ocular surgeries including laser-assisted in situ keratomileusis (LASIK)
 Photorefractive keratectomy (PRK)
Ophthalmic medication
 Antiglaucoma topical medication especially topical beta-adrenergic antagonists
 Benzalkonium chloride
Age
 Advanced age