Effects of Curcumin Treatment in a Diabetic Neuropathic Pain Model of Rats: Involvement of c-Jun N-Terminal Kinase Located in the Astrocytes and Neurons of the Dorsal Root Ganglion

<div>Western blot analysis of pJNK protein expression in the dorsal root ganglion (DRG). Total protein extraction from DRG was used for the western blot analysis. pJNK expression was increased in streptozotocin- (STZ-) induced diabetic neuropathic pain rats (STZ + Veh, <i>n</i> = 6), which was subsequently normalized by treatment with 50 mg/kg/day of curcumin (CMN) for 4 consecutive weeks (STZ + CMN50, <i>n</i> = 6). <i>ß</i>-Actin is a loading control.</div>

Pain Research and Management

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Figure 3: Effects of Curcumin Treatment in a Diabetic Neuropathic Pain Model of Rats: Involvement of c-Jun N-Terminal Kinase Located in the Astrocytes and Neurons of the Dorsal Root Ganglion 

Figure 3 | Effects of Curcumin Treatment in a Diabetic Neuropathic Pain Model of Rats: Involvement of c-Jun N-Terminal Kinase Located in the Astrocytes and Neurons of the Dorsal Root Ganglion 