Study on the Correlation between Pain and Cytokine Expression in the Peripheral Blood of Patients with Bone Metastasis of Malignant Cancer Treated Using External Radiation Therapy

Table 1

Clinical characteristics of patients.

No.	Age	Gender	Primary tumor	Antineoplastic agents	Analgesic drugs	Painful bone metastasis	Radiotherapy protocol
1	67	Female	Lung cancer	Icotinib	Tramadol, gabapentin, zoledronate	L3/4	10 MV-X line 3D-CRT DT 30 Gy/10 F
2	54	Male	Lung cancer	Osimertinib	Tramadol	C3/4	MLC 3DCR-T-SAD DT 30 Gy/10 F
3	68	Female	Lung cancer	Icotinib	Tramadol	Left ilium, left lip	10 MV-X line 3D-CRT DT 30 Gy/10 F
4	65	Male	renal cancer	Sorafenib	Tramadol	Left ilium	10 MV-X line 3D-CRT DT 30 Gy/10 F
5	69	Female	Lung cancer	Osimertinib	Tramadol	Right whirlbone	MLC 3DCR-T-SAD DT 30 Gy/10 F
6	66	Male	Lung cancer	Bicalutamide	Tramadol, zoledronate	Right lip	MLC 3DCR-T-SAD DT 30 Gy/10 F
7	70	Male	Lung cancer	Icotinib	Zoledronate	Right ilium	10 MV-X line 3D-CRT DT 45 Gy/15 F
8	62	Female	Lung cancer	—	Oxycodone	C4	10 MV-X line 3D-CRT DT 30 Gy/10 F
9	66	Female	Colorectal cancer	Bevacizumab	Tramadol, zoledronate	Left lip	10 MV-X line 3D-CRT DT 30 Gy/10 F
10	65	Female	Gallbladder carcinoma	—	Oxycodone	L3-5	MLC 3DCR-T-SAD DT 30 Gy/10 F
11	56	Female	Liver cancer	Regorafenib	Tramadol, gabapentin, zoledronate	Right ilium	10 MV-X line 3D-CRT DT 30 Gy/10 F
12	67	Male	Renal cancer	—	Tramadol	Right ilium	10 MV-X line 3D-CRT DT 30 Gy/10 F
13	64	Male	Colorectal cancer	—	Tramadol, gabapentin	Right ilium	10 MV-X line 3D-CRT DT 30 Gy/10 F
14	67	Male	Liver cancer	Gefitinib	Tramadol, gabapentin	T11	10 MV-X line 3D-CRT DT 30 Gy/10 F
15	46	Female	Liver cancer	Lenvatinib	Tramadol	S1, left ilium, left whirlbone	10 MV-X line IMRT PTV DT 50 Gy/20 F
16	74	Female	Lung cancer	Gefitinib	Tramadol, zoledronate	L5-S1	10 MV-X line IMRT GTV DT 30 Gy/10 F
17	53	Female	Lung cancer	Icotinib	Tramadol, zoledronate	Right arm	10 MV-X line 3D-CRT DT 30 Gy/10 F
18	38	Female	Ovarian cancer	Bevacizumab	Tramadol	L3	10 MV-X line 3D-CRT DT 30 Gy/10 F
19	57	Male	Lung cancer	Bevacizumab	Tramadol	T12, L1-4	10 MV-X line 3D-CRT DT 30 Gy/10 F
20	74	Female	Lung cancer	Teriprizumab	Oxycodone	L5	10 MV-X line IMRT PTV DT 30 Gy/10 F
21	86	Male	Lung cancer	—	Tramadol	T8/9	10 MV-X line IMRT PTV DT 45 Gy/15 F
22	55	Male	Liver cancer	Sorafenib	Oxycodone, gabapentin	Right clavicle, scapula, humerus	10 MV-X line 3D-CRT DT 30 Gy/10 F
23	61	Male	Prostate cancer	Bicalutamide	Tramadol	T10-L1	10 MV-X line 3D-CRT DT 30 Gy/10 F
24	59	Female	Lung cancer	Osimertinib	Tramadol	Left ilium	10 MV-X line IMRT PTV DT 33 Gy/11 F
25	55	Female	Breast cancer	Anastrozole	Tramadol, zoledronate	T11-L2	10 MV-X line IMRT PTV DT 30 Gy/10 F
26	72	Male	Lung cancer	—	Tramadol	Left femur	10 MV-X line IMRT PTV DT 45 Gy/15 F
27	61	Female	Colorectal cancer	—	Gabapentin	T12, L1-5	10 MV-X line 3D-CRT DT 30 Gy/10 F
28	69	Male	Lung cancer	Bevacizumab	Tramadol	T11/12	MLC 3DCR-T-SAD DT 30 Gy/10 F
29	60	Female	Lung cancer	Gefitinib	Tramadol, zoledronate	C5/6	10 MV-X line IMRT PTV DT 45 Gy/15 F
30	63	Male	Lung cancer	Cindillizumab	Tramadol	S1	10 MV-X line IMRT PTV DT 30 Gy/10 F