Antinociceptive Effects and Interaction Mechanisms of Intrathecal Pentazocine and Neostigmine in Two Different Pain Models in Rats

<div>(a-c). Intrathecal administration of the pentazocine-neostigmine mixtures attenuated the number of paw flinches in the formalin pain model. (d). Intrathecal administration of the pentazocine-neostigmine mixtures attenuated the mechanical allodynia in the plantar incision pain model. Each bar represents the mean ± SEM from 10 rats. 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Pain Research and Management

fig3

Figure 3

Figure 3: Antinociceptive Effects and Interaction Mechanisms of Intrathecal Pentazocine and Neostigmine in Two Different Pain Models in Rats 