Research Article

Site of Nerve Division Affects Pain-Related Behavior and Spinal Cord Glial Proliferation after C7 Neurotomy in a Rat Stroke Model

Table 1

Changes in pain-related behavioral testing and number of glial cells in the control and middle cerebral artery occlusion groups.

Control group (95% CI)MCAO group (95% CI)t/z

MPWT (mN)3.30 ± 2.42 (0.76–5.83)25.37 (22.02–25.37) (17.40–28.87)−2.99 (z)0.030
TPWT (s)9.53 ± 1.67 (7.78–11.29)10.13 ± 1.07 (9.01–11.26)−0.74 (t)0.477
Microglia (amount/mm2)21.50 ± 1.52 (19.91–23.09)20.33 ± 1.37 (18.90–21.77)1.40 (t)0.192
Astrocytes (amount/mm2)20.33 ± 1.03 (19.25–21.41)20.67 ± 1.21 (19.40–21.94)0.51 (t)0.619

n = 6 in each group; t value was calculated by the independent t-test; z value was calculated by the Mann–Whitney U test. CI, confidence interval; MPWT, mechanical paw withdrawal threshold; TPWT, thermal paw withdrawal threshold.