Research Article
Morphine in Combination with Ketamine Improves Cervical Cancer Pain and Suppresses Immune Function via the JAK3/STAT5 Pathway
Figure 4
Opioid antagonist naltrexone eliminates the inhibitory effects of morphine and ketamine on IL-2, IFN-γ, and IL-17 in vitro. (a) The level of IL-2 after naltrexone treatment measured by ELISA. (b) The level of IFN-γ after naltrexone treatment measured by ELISA. (c) The level of IL-17 after naltrexone treatment measured by ELISA. (d) The mRNA expression of IL-2 after naltrexone treatment detected by qRT-PCR. (e) The mRNA expression of IFN-γ after naltrexone treatment detected by qRT-PCR. (f) The mRNA expression of IL-17 after naltrexone treatment detected by qRT-PCR. vs. the control (PBS) group. vs. the morphine (PBS) group. vs. the Mor + Ket (PBS) group.
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