Neuroimaging Studies of Chronic Prostatitis/Chronic Pelvic Pain Syndrome

Table 1

Basic information for inclusion in the study.

No.	Author (year) country	Disease	Design	Sample capacity	Age	Intervention/control	Manipulation modality	Imaging modality	Analytical approaches	Cluster1 contribution degree	Cluster2 contribution degree
S1	Melissa A Farmer (2011) American; Farmer et al., 2011	CP/CPPS	Non-RCT	19/16	36.94	—	Resting state	DTI, T1-weighted MRI, rs-fMRI	Talairach space	1	0
S2	Livio Mordasini (2012); Switzerland; Mordasini et al., 2012	CP/CPPS	Non-RCT	20/20	40 ± 14	—	—	T1-weighted MRI	Talairach space	0	1
S3	Jason J kutch (2015) American; Kutch et al., 2015	CP/CPPS	Non-RCT	28/27	32.7 ± 1.5	—	Resting state; participants need to empty their bladders	rs-fMRI, T2-weighted MRI, T1-weighted MRI	MNI	6	0
S4	Yusong Lin (2017) China; Lin et al., 2017	CP/CPPS	Non-RCT	31/31	34.1 ± 10.3	—	Resting state, no spontaneous pelvic pain; the visual analog scale test must score 0 within 10 minutes before and after the MRI scan, respectively	rs-fMRI, T1-weighted MRI	MNI	1	2
S5	Christian Weisstanner (2017) Switzerland; Weisstanner et al., 2017	CP/CPPS	RCT	30 (therapy)/30 (sham therapy)	46 ± 14	Sono-electromagnetic/sham therapy; 12 weeks of treatment	Resting state	T1-weighted MRI, ASL, BOLD-MRI	MNI	0	1
S6	Yan Bai (2017) China; Bai et al., 2017	CP/CPPS	Non-RCT	19/19	34.8 ± 9.6	—	Resting state; the visual analog scale test must score 0 within 10 minutes before and after the MRI scan, respectively	Rs-fMRI	MNI	0	2
S7	Shengyang Ge (2021) China; Ge et al., 2021	CP/CPPS	Non-RCT	18/21	30.92 ± 7.69	—	Resting state; participants need to empty their bladders	rs-fMRI, T1-weighted MRI	MNI	0
S8	Xinfei Huang (2021) China; Huang et al., 2021	CP/CPPS	Non-RCT	19/32	38.11 ± 9.02	—	—	T1-weighted MRI, DTI	MNI	0	0
S9	Yan Xu (2021) China; Xu et al., 2021	CP/CPPS	Non-RCT	19/32	38.11 ± 9.02	—	—	T1-weighted MRI, DTI	MNI	0	0