Research Article

Correlation Analysis between Residual Pain after Vertebral Augmentation and the Diffusion Distribution of Bone Cement: A Retrospective Cohort Study

Table 1

Comparison between the groups.

Group A (n = 23)Group B (n = 13)95% CI value

Age (years), mean ± SD (range)76.30 ± 9.88 (63–98)74.38 ± 7.29 (62–84)−4.463 to 8.3030.545
Sex (male/female), n (%)2 (8)/21 (91)0 (0)/13 (100)0.274
Fracture segment
 Thoracic (T1-10)52
 Thoracolumbar (T11-L2)169
 Lumbar (L3-5)22
BMD (g/cm³), mean ± SD (range)−2.84 ± 0.32 (−3.7 to −2.5)−2.93 ± 0.41 (−3.9 to −2.5)−0.161 to 0.3360.480
Injection volume (ml), mean ± SD (range)6.11 ± 1.65 (4.0–10.0)5.15 ± 1.88 (3.0–9.0)−0.268 to 2.1770.122
Surgery time (min), mean ± SD (range)30.87 ± 8.02 (23–60)33.46 ± 8.43 (27–55)−8.351 to 3.1670.367
VAS (0–10), mean ± SD (range)
 Preoperation7.13 ± 0.76 (6–9)7.31 ± 0.86 (6–9)−0.736 to 0.3820.524
 2nd day postoperation3.17 ± 0.65 (2–5)3.85 ± 0.56 (3–5)−1.108 to −0.2360.004
 Last follow-up1.35 ± 0.57 (0–2)2.31 ± 0.75 (1–3)−1.412 to −0.508<0.001
ODI (0–100), mean ± SD (range)
 Preoperation77.65 ± 4.58 (68–88)75.23 ± 5.75 (64–88)−1.120 to 5.9630.174
 2nd day postoperation15.48 ± 4.14 (8–22)20.77 ± 4.67 (14–28)−8.346 to −2.2360.001
 Last follow-up10.52 ± 3.78 (2–16)14.77 ± 3.52 (10–20)−6.847 to −1.6480.002
IVH (mm), mean ± SD (range)
 Preoperation16.32 ± 3.82 (9.52–22.31)16.81 ± 3.21 (12.04–24.37)−3.040 to 2.0610.699
 2nd day postoperation18.74 ± 4.56 (11.63–28.49)18.83 ± 3.75 (14.00–26.21)−3.121 to 2.9330.950
 Last follow-up18.87 ± 4.26 (13.56–26.56)18.87 ± 3.47 (13.63–25.63)−2.822 to 2.8180.999
LKA (°), mean ± SD (range)
 Preoperation18.44 ± 8.28 (3.19–34.90)15.18 ± 10.41 (0.04–30.61)−3.142 to 9.6780.308
 2nd day postoperation14.89 ± 8.76 (2.82–32.45)13.17 ± 7.99 (2.36–28.51)−4.269 to 7.7110.563
 Last follow-up16.11 ± 9.65 (3.65–36.32)14.28 ± 8.68 (2.65–28.64)−4.739 to 8.4080.574
Vertebral body volume (cm³), mean ± SD (range)29.86 ± 7.99 (15.96–43.97)33.81 ± 9.27 (18.77–45.12)−9.921 to 2.0160.187
Bone cement volume (cm³), mean ± SD (range)7.08 ± 2.25 (3.23–11.36)5.14 ± 1.60 (2.61–7.27)0.501 to 3.3810.010
Volume ratio (%)23.7015.11<0.001

Note: BMD, bone mineral density; VAS, visual analog scale; ODI, Oswestry disability index score; IVH, injured vertebral height; LKA, local kyphosis angle.