Research Article

Association of COMT Val158Met Polymorphism with Fibromyalgia in Khartoum State, Sudan

Table 3

The variation in genotype frequency of COMT Val158Met with disease status.

GenotypeDisease status
FM (N = 20)RH (N = 10)Healthy (N = 10)Fisher exact test

HH (Val/Val)0% (N = 0)50% (N = 5)0% (N = 0)value = 0.033
HL (Val/Met)65% (N = 13)50% (N = 5)100% (N = 10)
LL (Meth/Met)35% (N = 7)0% (N = 0)0% (N = 0)

HH represents the genotype of normal homozygous (Val/Val); HL represents the heterozygous (Val/Met); LL represents the mutant homozygous (Meth/Met); FM: fibromyalgia patients; RH: rheumatoid patients.