Soluble Epoxide Hydrolase Inhibitor TPPU Alleviates Nab-Paclitaxel-Induced Peripheral Neuropathic Pain via Suppressing NF-κB Signalling in the Spinal Cord of a Rat

Figure 2

Inhibition of sEH-protected axons from nab-paclitaxel treatment. Pathological changes in axons were evaluated by immunohistochemistry of NF-L, NF-M, NF-H, and β-APP. Scale bars = 100 μm. n = 6; compared to the control group, ^# compared to the nab-P group. Black arrows indicate the NF-L, NF-M, NF-H, and β-APP positive cells, respectively.