Molecular Characterization of Putative Chordoma Cell Lines

Table 2

Characteristics of cell lines.

Cell line	Growth pattern	Expression array pattern	aCGH	Brachyury expression	CD24 expression
U-CH1	Physaliferous	Chordoma-like	Multiple CNV	Positive	Positive
U-CH2	Physaliferous	Chordoma-like	Multiple CNV	Positive	Positive
K001*	Physaliferous	Chordoma-like		Positive	Positive
CCL3**	Spindle	Inadequate	Inadequate		Negative
CCL4	Spindle	Not chordoma-like	Normal	Negative	Negative
GB60	Spindle	Not chordoma-like	Normal	Low RNA; negative protein	Negative
CM-319	Polygonal	Not chordoma-like	Multiple CNV	Negative	Positive

*K001 was partially characterized before the cell line was lost
**CCL3 is of nonhuman origin
IVD = intervertebral disc tissue