|
| Symbol | Gene name | 5-AZA upregulated? | Downregulated in EWS primary tumors? |
|
| ACVR1C | Activin a receptor, type ic | No | * |
| AXL | Axl receptor tyrosine kinase | Yes | Yes |
| CALCA | Calcitonin/calcitonin-related polypeptide, alpha | Yes | No |
| CCNA1 | Cyclin a1 | Yes | NS |
| CD9 | Cd9 antigen (p24) | Yes | No |
| COL1A1 | Collagen, type 1, alpha 1 | Yes | Yes |
| CYP1B1 | Cytochrome p450, family 1, subfamily b, polypeptide 1 | Yes | Yes |
| DDB2 | Damage-specific DNA-binding protein 2 | No | No |
| E2F5 | EF transcription factor 5, p130 binding | No | No |
| ELK3 | ETS-domain protein (SRF accessory protein 2) | Yes | No |
| EPHA3 | Eph receptor a3 | Yes | No |
| ESR1 | Estrogen receptor 1 | No | No |
| FZD9 | Frizzled homolog 9 | Yes | No |
| HIF1A | Hypoxia inducible factor 1, alpha subunit | No | Yes |
| HOXB13 | Homeobox b13 | No | No |
| HS3ST2 | Heparan sulfate 3-O-sulfotransferase 2 | Yes | NS |
| HTR1B | 5-hydroxytryptamine receptor 1B | No | NS |
| ITGA6 | Integrin, alpha 6 | No | Yes |
| LYN | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog | Yes | Yes |
| MAP3K1 | Mitogen-activated protein kinase 1 | Yes | * |
| MME | Membrane metalloendopeptidase | No | Yes |
| MMP2 | Matrix metallopeptidase 2 | No | Yes |
| NGFR | Nerve growth factor receptor | Yes | No |
| NTRK2 | Neurotrophic tyrosine kinase, receptor, type 2 | No | No |
| RARRES1 | Retinoic acid receptor responder 1 | Yes | No |
| RYK | Ryk receptor-like tyrosine kinase | No | Yes |
| SEPT5 | Septin 5 | No | No |
| SERPINE1 | Serpin peptidase inhibitor, clade e, member 1
(nexin, PAI1) | Yes | Yes |
| SMARCB1 | Swi/snf-related, matrix-associated, actin-dependent
regulator of chromatin, subfamily b | No | No |
| SOX17 | Sry (sex determining region y)-box 17 | Yes | No |
| TFAP2C | Transcription factor AP gamma | Yes | NS |
| TGFBI | Transforming growth factor, beta-induced, 68 kda | No | Yes |
| TNK1 | Tyrosine kinase, nonreceptor, 1 | No | NS |
| UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1 | Yes | No |
| VCAN | Chondroitin sulfate proteoglycan core protein 2 (versican) | Yes | Yes |
| WNT5A | Wingless-type MMTV integration site family, member 5A | No | No |
|
