Clinical Study

Quality of Life and Utility in Patients with Metastatic Soft Tissue and Bone Sarcoma: The Sarcoma Treatment and Burden of Illness in North America and Europe (SABINE) Study

Table 4

EQ-5D utility values and VAS scores by health state.

StatisticEQ-5D utility1VAS score2

Health state 1N1717
1st-line chemotherapyMean (SD)0.72 (0.31)68.82 (14.44)
Median0.7670
Min, max−0.08, 130, 85
95% CI0.56, 0.8861.4, 76.25
Health state 2N2223
2nd-line chemotherapyMean (SD)0.64 (0.33)65.04 (18.91)
Median0.7370
Min, max−0.08, 115, 85
95% CI0.49, 0.7856.86, 73.22
Health state 3N1212
3rd-line chemotherapyMean (SD)0.77 (0.14)63.75 (17.9)
Median0.7564
Min, max0.59, 140, 90
95% CI0.68, 0.8652.38, 75.12
Health state 4N2828
Progressive diseaseMean (SD)0.56 (0.27)50.79 (22.55)
Median0.6650
Min, max0.08, 10, 100
95% CI0.46, 0.6742.04, 59.53
Health state 5N3536
Off chemotherapy, preprogressionMean (SD)0.77 (0.14)74.56 (16.03)
Median0.7677
Min, max0.52, 139, 100
95% CI0.73, 0.8269.13, 79.98

Note: 1Utility values range from −0.59 (worse than death)—1 (full health); 2VAS score range-from 0 to 100.