High Dose Thiotepa in Patients with Relapsed or Refractory Osteosarcomas: Experience of the SFCE Group

Table 2

Patient characteristics at the time of relapse or progression treated with high dose thiotepa.

	Number of patients	%
Patient characteristics
Age, years
Median	15.9
Range	4 to 31
Disease status at study entry
Refractory disease	2	4.4
First relapse	26	57.8
Subsequent relapse	17	37.8
Site of last relapse
Lung only	23	51
Lung + another site	15	33
Bone only	1	2.2
Other	4	9.3
Relapse operability
Operable	20	46.5
Inoperable	23	53.5
Missing value	2
Radiological response
Partial response	12	30.8
Stable disease	18	46.2
Progressive disease	9	23.1
Not evaluable	6
Histological response after thiotepa
Good response	9	29.0
Poor response	22	71.0
No surgery	14