Endosialin and Associated Protein Expression in Soft Tissue Sarcomas: A Potential Target for Anti-Endosialin Therapeutic Strategies

Figure 1

Expression of endosialin and PDGFR-β across numerous solid tumors. Gene expression of endosialin and PDGFR-β was evaluated across all tumor types in the Total Cancer Care® (TCC) Data Warehouse in a total of 15,820 samples. The distribution of the expression level in each tumor type is represented by box plots, with the middle horizontal line representing the median and the box representing the 25th to 75th percentiles. (a) Endosialin in primary tumors; (b) endosialin in metastatic tumors; (c) PDGFR-β in primary tumors; and (d) PDGFR-β in metastatic tumors. Both endosialin and PDGFR-β are highly expressed in soft tissue tumors which are mostly comprised of sarcomas.

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