Establishment of an Academic Tissue Microarray Platform as a Tool for Soft Tissue Sarcoma Research

Table 2

Special subtype-specific tissue microarrays for (longitudinal) tumor biology studies.

Name of tissue microarrays	Soft tissue sarcoma subtypes	Different stages of samples in pairs	Number of cases
UZL_TMA_CCSA	Clear cell sarcoma	Primary tumor, metastatic lesion, and/or local recurrence	5
UZL_TMA_ASPS	Alveolar soft part sarcoma	Primary tumor and metastatic lesions	2
UZL_TMA_ARMS	Alveolar rhabdomyosarcoma	Primary tumor, metastatic lesion, and/or local recurrence	4
UZL_TMA_LMS	Leiomyosarcoma	Primary tumor, metastatic lesion, and/or local recurrence	36
		Different types of mutations
UZL_TMA_GIST	Gastrointestinal stromal tumor	KIT exon 9	9
		KIT exon 11 deletion including codons 557/558	10
		KIT exon 11 substitutions	9
		KIT exon 11 duplication	7
		KIT exon 11 deletion outside codons 557/558	5
		KIT exon 11 + 17	5
		KIT exon 11 + 13	4
		KIT exon 11 p. W557_K558 deletion on codon 557–558	4
		PDGFRA p. D842 V	7
		PDGFRA other exon 18 mutation	5
		No KIT/PDGFRA mutation	7
		Different subgroups of LPS
UZL_TMA_LPS	Liposarcoma	Well differentiated	14
		Dedifferentiated	11
		Myxoid/round cell	10
		Pleomorphic	6

PDGFR-A: platelet-derived growth factor receptor-alpha.