Predictors of Recurrence and Patterns of Initial Failure in Localized Ewing Sarcoma: A Contemporary 20-Year Experience

Table 1

Patient, tumor, and treatment characteristics of localized Ewing sarcoma cohort.

		No relapse	Relapse
Number of patients		73	21
Age at diagnosis	Median age	15.8 years	21.1 years
	<10 y	19 (26%)	1 (5%)
	10–21 y	24 (33%)	9 (43%)
	>21 y	30 (41%)	11 (52%)
Primary tumor site	Appendicular	18 (25%)	6 (29%)
	Axial	38 (52%)	11 (52%)
	Extraosseous	17 (23%)	4 (19%)
Primary tumor size	Median size	6.4 cm	8.5 cm
	Mean size	7.1 cm	9.5 cm
	≤5 cm	25 (34%)	5 (24%)
	5.1–9.9 cm	31 (42%)	6 (29%)
	≥10 cm	14 (19%)	8 (38%)
	Unknown	3 (4%)	2 (10%)
Definitive treatment	Surgery alone	42 (58%)	9 (43%)
	RT alone	13 (18%)	5 (24%)
	Surgery + RT	18 (25%)	7 (33%)
Percent necrosis	≥95%	27 (37%)	2 (10%)
	<95%	14 (19%)	10 (48%)
	Unknown or N/A	32 (44%)	9 (43%)