Sarcoma of the Breast: Clinical Characteristics and Outcomes of 991 Patients from the National Cancer Database

Table 6

Overall survival associated with clinicopathologic characteristics, the Cox proportional hazard model.

Characteristics	Number	HR	95% CI
Age
≤50	275	1	NA	NA
51–75	472	1.45	1.10–1.92	0.008
75<	169	4.41	3.30–5.93	<0.001
Treatment facility
Academic/research	294	1	NA	NA
Community hospital	510	1.30	1.03–1.63	0.024
Tumor grade
Well differentiated	96	1	NA	NA
Moderately differentiated	110	1.60	0.91–2.82	0.101
Poorly differentiated/undifferentiated	459	2.99	1.87–4.87	<0.001
T stage
T1	452	1	NA	NA
T2	212	2.52	1.93–3.28	<0.001
T3	78	3.61	2.54–5.12	<0.001
T4	74	3.99	2.81–5.64	<0.001
N stage
N0	310	1	NA	NA
N1	21	3.34	1.91–5.83	<0.001
M stage
M0	785	1	NA	NA
M1	73	6.51	4.90–8.65	<0.001
Surgery
Yes	829	1	NA	NA
No	87	2.87	2.13–3.85	<0.001
Surgical margins
Negative (R0)	720	1	NA	NA
Positive	70	2.40	1.73–3.33	<0.001
Radiation
Yes	265	1	NA	NA
No	651	1.28	1.01–1.62	0.038
Chemotherapy
Yes	171	1	NA	NA
No	745	0.69	0.54–0.88	0.003

NA, not applicable.