|
| Minor discrepancies |
| Benign |
| | Institution A | Institution B |
|
| L107 | Fibroblastic/myofibroblastic proliferates in predominantly tight connective tissue with partly regressive changes. | Collagen-rich myofibroblastic proliferation |
| L108 | Chondrogenic neoplasm, highly differentiated | Enchondroma |
| L198 | Fibrin and blood, intercalated with some lamellar bone tissue and connective tissue | Intraosseous ganglion |
| Intermediate |
| | Institution A | Institution B |
| L31 | Spindle-cell, partly multinucleated giant-cell tumor with osteoid formation | Aneurysmal bone cyst |
| L34 | Giant cell tumor of the soft tissue | Plexiform fibrohistiocytic tumour |
| L112 | Chondroid neoplasia with cancellous bone | Epiphyseal atypic chondrogenic tumor |
| Malignant |
| | Institution A | Institution B |
| L4 | Spindle-cell high-grade sarcoma | Spindle and pleomorphic high-grade malignant unclassified sarcoma G3 |
| L11 | Spindle-cell pleomorphic sarcoma, high grade, with evidence of myogenic differentiation | Leiomyosarcoma |
| L19 | Epithelioid sarcoma (proximal type) | Epithelioid angiosarcoma |
| L29 | Lymph node metastasis of a solid tumor (differential diagnosis: clear cell sarcoma or malignant melanoma) | Lymph node metastasis of malignant melanoma |
| L35 | Pleomorphic undifferentiated sarcoma with necrosis zones | Pleomorphic liposarcoma (G3) |
| L60 | Spindle-cell pleomorphic neoplasia with striated muscles | Sclerosing epithelioid fibrosarcoma |
| L63 | Sarcoma, spinel and partly pleomorphic cells | Spindle and pleomorphic cell soft tissue sarcoma at least G2 with FNCLCC score of 4 |
| L64 | Highly differentiated liposarcoma | Dedifferentiated liposarcoma with low-grade dedifferentiated portion, malignancy grade at least G2 |
| L84 | Myxofibrosarcoma | Undifferentiated spindle cell sarcoma |
| L110 | Myxofibrosarcoma (high grade) | High-grade, unclassifiable spindle cell sarcoma (G2) |
| L140 | Undifferenciated pleomorphic sarcoma | High-grade, unclassifiable spindle cell sarcoma (G2) |
| L157 | Myxofibrosarcoma, high grade | High-grade, unclassifiable spindle cell sarcoma (G2) |
| L188 | Pleomorphic highly proliferative tumor | Giant cell-rich leiomyosarcoma at least G2 |
| L201 | Myxofibrosarcoma (high grade) | Spindle cell sarcoma at least G2 |
|
| Major discrepancies |
| Benign |
| | Institution A | Institution B |
|
| L2 | Fat necrosis | PHAT (pleomorphic hyalinizing angiectatic tumor of soft parts) |
| L37 | Fibrin-rich connective tissue with low chronic inflammation and regressive changes | Nodular fasciitis |
| L52 | Mature teratoma/dermoid | Spinal dermoid cyst |
| L57 | Spindle-cell mesenchymal myofibroblastic proliferation with low MIB-1 proliferation rate along with skeletal muscles | Intramuscular myxoma |
| L66 | Parts of a spindle-cell myxoid-chondroid impinging neoplasia | Benign portion of a peripheral nerve sheath tumor |
| L109 | Slightly atypical spindle cell tumor with myxoid background and increased proliferation (Ki67) of approx. 30%. | Myofibroblastic proliferation of the nodular fasciitis type |
| L113 | Low-grade fibromyxoid sarcoma | Intramuscular myxoma |
| L145 | Smooth-muscular proliferation with scaly calcifications as well as circumscribed ossification without necrosis or evidence of mitoses | Leiomyoma of the deep somatic soft tissues |
| L195 | Intramuscular lipoma | Intramuscular haemangioma |
| Intermediate |
| | Institution A | Institution B |
| L100 | Spindle cell mast cell-rich proliferation with low proliferation rate and immunohistochemically S-100 positive with negativity for SOX-10 | Solitary fibrous tumor (SFT) |
| L101 | Plump spindle-cell tumour with multiple multinucleated giant cells | Periosteal aneurysmal bone cyst (ABC) |
| L117 | Cell-rich neoplasia of oval, plump spindle mononuclear cells intermixed with giant cells and haemorrhage residues in connective tissue. | Tenosynovial giant cell tumor of the diffuse type |
| Malignant |
| | Institution A | Institution B |
| L1 | Epithelioid sarcoma | Angiosarcoma |
| L6 | Osteosarcoma | Chondrosarcoma |
| L7 | Highly differentiated/dedifferentiated or a myxoid liposarcoma | Dedifferentiated liposarcoma (low grade) |
| L51 | Myxoid chondrosarcoma | Myxoid liposarcoma (G1) |
| L70 | Chondroid and focal spindle cell neoplasia | Mesenchymal chondrosarcoma |
| L76 | Slightly hypercellular chondrogenic tissue, connective tissue and skeletal muscle | Conventional chondrosarcoma |
| L94 | Pleomorphic liposarcoma | Round cell liposarcoma G3 |
| L150 | Small blue round cell tumor with low proliferation (Ki67) of approx. 10-15%. | Granulosa cell tumor |
| L164 | Atypical lipomatous tumor/well-differentiated liposarcoma | Dedifferentiated liposarcoma, at least G2 |
| L171 | Neoplasia, predominantly spindle cell in cancellous bone with focal evidence of irregular osteoid. | Osteosarcoma, high grade |
| L191 | Infiltrates of small, round and blue cell neoplasia | Poorly differentiated neuroendocrine carcinoma (Merkel cell carcinoma) |
| L204 | Spindle and pleomorphic cell neoplasm with myxoid background of partial expression of MDM2 | High-grade myxofibrosarcoma (G2-3) |
|
