Morphological Characteristics of Young and Old Murine Hematopoietic Stem Cell Niches, as Modeled In Vitro

Figure 3

Light micrographs of representative cell types of a hematopoietic stem cell (HSC) niche investigated using a phase-contrast light microscope (200x) after four weeks of culturing. Adipocytes with lipid droplets, seen as round structures of different sizes, are indicated with a red arrow (a); fibroblast and mesenchymal stromal cells (MSCs) are characterized by a flattened and elongated shape (b); endothelial cells growing in lines are indicated with a blue arrow (c).