Morphological Characteristics of Young and Old Murine Hematopoietic Stem Cell Niches, as Modeled In Vitro

Figure 7

SEM micrographs of different, morphologically distinct cell types in young and old hematopoietic stem cell (HSC) niches. (a–c) Flattened cells with a folded central area ((a, c) round; (b) oval) ((a, c) cells with a low number of short filopodia; (b) cell with a large number of filopodia) and differing cell surface roughness ((a, b) cells with rough membrane surfaces; (c) cell with smooth membrane surface). (d–f) Round-shaped cells with a large number of filopodia (d), extended lamellipodium (e), and visible cellular protrusions (f). (g) Adipocyte filled with numerous lipid droplets. (h) elongated cell. Scale  μm.