| | Males | Females | Time effect | Gender effect | Time gender effect | | Mean (SD) | Mean (SD) |
| Speed of processing | | | | | | Baseline | 23.2 (14.2) | 21.8 (13.5) | , df = 2,55, | , df = 1,55, | , df = 2,55, | Month 3 | 29.2 (10.8) | 31.5 (12.1) | Month 6 | 32.7 (12) | 32.8 (16.1) |
| Attention/vigilance | | | | | | Baseline | 23.1 (8) | 20.2 (9.3) | , df = 2,51, | , df = 1,51, | , df = 2,51, | Month 3 | 28.3 (9.7) | 30.0 (8.1) | Month 6 | 30.4 (9.1) | 36.8 (7.5) |
| Working memory | | | | | | Baseline | 31.2 (10.6) | 24.4 (14.3) | , df = 2,55, | , df = 1,55, | , df = 2,55, | Month 3 | 35.6 (8.7) | 31.7 (11.6) | Month 6 | 38.1 (9.8) | 35.2 (11.5) |
| Verbal learning | | | | | | Baseline | 34.9 (9.7) | 35.7 (7.6) | , df = 2,55, | , df = 1,55, | , df = 2,55, | Month 3 | 38.4 (10.1) | 40.1 (8.2) | Month 6 | 40.6 (10.3) | 42 (6.9) |
| Visual learning | | | | | | Baseline | 37.1 (12.2) | 32.9 (12.6) | , df = 2,55, | , df = 1,55, | , df = 2,55, | Month 3 | 42 (12.1) | 42.5 (10.7) | Month 6 | 43.6 (10.6) | 44.6 (10.5) |
| Reasoning and problem solving | | | | | | Baseline | 37.1 (5.4) | 37.2 (7.7) | , df = 2,55, | , df = 1,55, | , df = 2,55, | Month 3 | 40.1 (6.2) | 38.1 (4.5) | Month 6 | 44.1 (9.0) | 39.9 (5.8) |
| Social cognition | | | | | | Baseline | 30.9 (9.9) | 28.3 (9.1) | , df = 2,52, | , df = 1,52, | , df = 2,52, | Month 3 | 27.5 (9.6) | 30.6 (13.2) | Month 6 | 27.4 (9.2) | 36.3 (12.9) |
| Overall composite | | | | | | Baseline | 20.6 (10.7) | 19.6 (10.9) | , df = 2,49, | , df = 1,49, | , df = 2,48, | Month 3 | 25.7 (10.3) | 28.8 (9.8) | Month 6 | 29.2 (10.7) | 33.7 (8.8) |
|
|