Inducible Protective Processes in Animal Systems XIII: Comparative Analysis of Induction of Adaptive Response by EMS and MMS in Ehrlich Ascites Carcinoma Cells

Table 2

Frequency of chromosomal aberrations observed after conditioning, challenging, and combined treatments of EMS in EAC cells at 48 h and 72 h recovery times.

Recovery time (h)	Treatment	Chromosomal aberrations		Total aberrations
		Chromatid type	Chromosome type
48	Control	7.33±0.67	—	7.33±0.67^a (2.44)
	Conditioning	32.67±0.88	3.00±0.58	35.67±1.45^b (11.89)
	Challenging	143.00±5.51	14.33±2.03	157.33±7.31^c (52.44)
	Combined	106.67±1.86	11.67±1.76	118.33±2.96^d (39.44)
72	Control	8.00±1.16	—	8.00±1.16^a (2.67)
	Conditioning	25.33±2.33	1.33±0.33	26.66±2.60^b (8.89)
	Challenging	118.67±1.86	12.00±1.53	130.67±2.96^e (43.56)
	Combined	84.00±3.79	7.33±1.20	91.33±4.98^f (30.44)

Note: average data of 3 independent experiments; 3 animals per experiment were used; 100 cells per animal scored; and a total of 900 cells scored per dose. Values with same superscripts are not significantly different (𝑃>0.05), whereas values with different superscripts are significantly different (𝑃<0.05) from one another. Parentheses show the percentage of total aberrations.