Enhancement of Mycophenolate Mofetil Permeation for Topical Use by Eucalyptol and N-Methyl-2-pyrrolidone

Table 1

The skin permeation flux and lag time of MMF and MPA at various concentrations of MMF preparations.

MMF concentration (μg/mL)		Flux (μg/h/cm^2)	Lag time (h)
36	MMF	0	0
	MPA	0	0
76	MMF	0	0
	MPA	0.37 ± 0.10	12
160	MMF	0	0
	MPA	0.61 ± 0.07	6
300	MMF	0.23 ± 0.05	12
	MPA	0.78 ± 0.03	6

Results are expressed as the mean ± SD of at least three experiments. There was a significant different value of skin permeation flux of MPA, when compared among various concentrations of MMF solution (76, 160, and 300 μg/mL).