Review Article

Medicinal Effect, In Silico Bioactivity Prediction, and Pharmaceutical Formulation of Ageratum conyzoides L.: A Review

Table 1

Seven compounds which would be predicted to interact molecularly with the respective protein target leading to their drug effect to the corresponding diseases.

LigandsProtein targetDisease target

Precocene ICyclooxygenase-2Pain
MMP-9Rheumatoid arthritis

Precocene IICyclooxygenase-2Pain
MMP-9Rheumatoid arthritis

VMDCCyclooxygenase-2Pain
MMP-9Rheumatoid arthritis

Beta-sitosterolTyrosinaseAntioxidant
Glycoside hydrolaseHyperglycemic
4-Diphosphodicytidyl-2-C-methylerythritolAntibacteria

StigmasterolHuman p53, MMP-9Cancer
TyrosinaseAntioxidant
Glycoside hydrolaseHyperglycemic
4-Diphosphodicytidyl-2-C-methylerythritolAntibacteria

5-MethoxynobiletinMMP-9Rheumatoid arthritis
Ornithine delta-aminotransferaseAntimalaria

LycopsamineOrnithine delta-aminotransferaseAntimalaria