Research Article
Phytochemical Study and Antibacterial and Antibiotic Modulation Activity of Punica granatum (Pomegranate) Leaves
Table 4
Antibiotic modulation activity of P. granatum leaf extracts by checkerboard method (FIC index).
| | Extract | Staphylococcus aureus | Escherichia coli | | Penicillin-resistant strain | Methicillin-resistant strain | Penicillin-resistant strain | Multidrug-resistant strain | | Amoxicillin | Cefotaxime | Amoxicillin | Cefotaxime | Amoxicillin | Cefotaxime | Amoxicillin | Cefotaxime |
| | Chloroform extract | 1 | — | 2 | 2 | 1 | — | 2 | 1 | | Ethyl acetate extract | 2 | — | 2 | 2 | 1 | — | 2 | 1 | | Ethanol extract | 0.25 | — | 2 | 1 | 2 | — | 2 | 1 | | Aqueous extract | 0.25 | — | 2 | 1 | 0.5 | — | 2 | 0.5 | | TOF extract | 0.125 | — | 2 | 0.5 | 0.125 | — | 2 | 0.5 |
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