Antimalarial Activity of Extract and Fractions of Sauropus androgynus (L.) Merr.

Table 3

Percentages of inhibition of parasite growth in mice infected with P. berghei treated orally by doses of ethanolic leaf extract of S. androgynus for four consecutive days before infection (D₀−D₃).

Treatments	Dose (mg/kg/day)	% Parasitaemia		% Inhibition
		Day 6	Day 10
Na CMC	—	0.26 ± 0.26	11.65 ± 1.50	—
Ethanolic leaf extract of S. androgynus	100	1.16 ± 0.39	6.61 ± 1.06	43.36 ± 18.38
	200	0.73 ± 0.27	5.70 ± 1.27	51.07 ± 21.77
	400	0.58 ± 0.38	3.76 ± 0.48	67.74 ± 9.21
Doxycycline	13	0.20 ± 0.12	3.52 ± 0.44	69.75 ± 8.51

Data are expressed as mean ± SEM; n = 5; significance relative to the negative control, .